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These reveal relevant electrolytical disturbances, including K, Ca, Ph, Mg…, as well as inside-outside temperature imbalances.
Authorities advocate correctly increasing Mg input, but frequently omitting the other ones.
Many people for one reason or the other are not exposed to sufficient sunrays, with low Vitamin D as a result.
If this is the case, you can replenish body stores by taking pills or drops with this vitamin.
MC happen also at temperature imbalances (too cold, or too warm), and that is why most frequently the calf muscles are concerned.

