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“Peace begins with a smile…”

Mother Teresa, born Anjezë Gonxhe Bojaxhiu (1910 –1997), Albanian-Indian Catholic nun and the founder of the Missionarities of Charity.

Science advances at a huge pace.

A few facts known since recently:

1. Physical exercise is able not only to generate new connections between exisisting nerve cells, but even to foster such ones from the framework.

2. There are three types ketone bodies, two which develope sphyngo-lipids, and one which dissolves fat. Ketone bodies are produced in liver cells by the breakdown of fatty acids. Unlike free fatty acids, ketone bodies can cross the blood-brain barrier and are therefore available as fuel for the cells of the CNS, acting as a substitute for glucose, on which these cells normally survive. Ketone bodies are readily transported into tissues outside the liver, where they are converted into acetyl-CoA(acetyl-Coenzyme A)—which then enters the citric acide cycle (Krebs cycle) and is oxidized for energy. These liver-derived ketone groups include acetoacetic acid (acetoacetate), beta-hydroxybutyrate, and acetone, a spontaneous breakdown product of acetoacetate. Ketone bodies are produced by the liver during periods of caloric restriction of various scenarios.  They are released into the blood after glycogen stores in the liver have been depleted. Ketone bodies are also produced in glial cells under periods of food restriction to sustain memory formation. During the initial stages of ketosis, the brain does not burn ketones, since they are an important substrate for lipid synthesis in the brain. Furthermore, ketones produced from Omega 3 Fatty Acids may reduce cognitive deteriortion in old age. (From Wikipedia).

Here we should refer to a few well-known facts: -All those Disorders are rare in childhood and adolescence, appear during adulthood, and become common in third age.

Hence, they are probably tightly linked with our Lifestyle!

A. Eating for instance three heavy meals every single day does not give the body enough time to burn an use this abundant substrate.

There is No Time for Ketone Bodies Production. Hence no occasion for Sphyngo-Lipids development in NS.

B. A sedentary life does not allow new connections in NS to occur.

Alzheimer Disease is for instance classified as Diabetes mellitus Type 3!

Physical exercise is advocated by many for treatment of Parkinson’s. With a lot of success, I must say!

In Antiquity fasting was used regularly for therapy of all kinds of illnesses. Nowadays athletes practice it for coming to a better shape.